We know from other countries and contexts that aspiring authoritarians often target scientists, elevate loyalists, and suppress or sideline any who might have the knowledge, expertise, or power to challenge government transgression and failures to make science-based policy decisions. In response to such threats, the US scientific community can work to rebuild critical elements of the federal science enterprise now being dismantled or compromised, including science advisory committees and scientific assessments, which for decades have helped ensure that the best available science informs policy decisions.