CRISPR Gene Editing in Human Embryos Wreaks Chromosomal Mayhem
Three studies showing large DNA deletions and reshuffling heighten safety concerns about heritable genome editing.
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Three studies showing large DNA deletions and reshuffling heighten safety concerns about heritable genome editing.
Achieving the global benefits of artificial intelligence (AI) will require international cooperation on many areas of governance and ethical standards, while allowing for diverse cultural perspectives and priorities.
The prestige ranking of scholarly journals is costly to science and to society.
This publication shows how a single paper affects the impact factor (IF) of a journal by analyzing data from 3,088,511 papers published in 11639 journals in the 2017 Journal Citation Reports of Clarivate Analytics.
This study aims to evaluate the 1-year results of a prospective randomized social media trial to determine the effect of tweeting on subsequent citations and non-traditional bibliometrics.
COVID-19 is a major acute crisis with unpredictable consequences. Many scientists have struggled to make forecasts about its impact. However, despite involving many excellent modelers, best intentions, and highly sophisticated tools, forecasting efforts have largely failed.
Study found that preliminary criterion scores fully account for racial disparities - yet do not explain all of the variability - in preliminary overall impact scores.
Personal integrity and local culture are key to research integrity, and bullying and harassment is the single biggest negative influence, according to a new study by UK Research and Innovation (UKRI).
The research world has moved faster than many would have suspected possible in response to the COVID-19 pandemic. In five months, a volume of work has been generated that even the most intensive of emergent fields have taken years to create.In our new report, How COVID-19 is Changing Research Culture, we investigate the research landscape trends and cultural changes in response to COVID-19. The report includes analysis of publication trends, geographic focal points of research, and collaboration patterns.
What was the impact of non-pharmaceutical interventions at the outset of the pandemic?
England is abandoning lockdown and possibly hope of containing a second wave of covid-19.
In the midst of the COVID-19 pandemic, science is crucial to inform public policy. At the same time, mistrust of scientists and misinformation about scientific facts are rampant. Six scientists, actively involved in outreach, reflect on how to build a better understanding and trust of science.
Predatory publishing has emerged as a professional problem for academics and their institutions, as well as a broader societal concern, bringing to the fore a debate over what constitutes legitimate science.
A public-private partnership and platform for harmonized clinical trials aims to accelerate licensure and distribution.
Authors, editors and publishers differ in their understanding of and the value they attach to the purposes of peer review.
Explanation of the differences between confirmatory and exploratory research and the dangers of confusing the two concepts.
We have developed an analysis pipeline to facilitate real-time mutation tracking in SARS-CoV-2, focusing initially on the Spike (S) protein because it mediates infection of human cells and is the target of most vaccine strategies and antibody-based therapeutics.
New sources of citation data have recently become available. Although these have been compared to the Web of Science (WoS), Scopus, or Google Scholar, there is no systematic evidence of their differences across subject categories. In response, this paper investigates citations found by these data sources to English-language highly-cited documents published in 2006 from 252 subject categories, expanding and updating the largest previous study.
Peer review is embedded in the core of our knowledge generation systems. Despite its critical importance, it curiously remains poorly understood in a number of dimensions. In order to address this, this paper assesses where the major gaps in the theoretical and empirical understanding of peer review lie.
The objective of this review is to identify all preprint platforms with biomedical and medical scope and to compare and contrast the key characteristics and policies of these platforms.
The study replicates the NIPS experiment of 2014, showing that the ratings of peer review are not robust, and that altering reviewers leads to a dramatic impact on the ranking of the papers. This paper also shows that innovative works are not highly ranked in the existing peer review process, and in consequence are often rejected.
The world is experiencing a major pandemic with a high mor-tality. One can hope that the outbreak will end spontaneously aftermost people are infected, but the SARS-2 coronavirus may becomeendemic and continue to cause cycles of respiratory disease andfatal pneumonias.
It is urgent to understand the future of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) transmission. This research group used estimates of seasonality, immunity, and cross-immunity for betacoronaviruses OC43 and HKU1 from time series data from the USA to inform a model of SARS-CoV-2 transmission.
The postdoctoral experience is in need of reform. Here the authors outline concrete steps that institutions, postdocs and mentors can take to improve the landscape.
Confused about mask wearing? Sure, it’s complicated. But not as complicated as some people imply.
Data makes science possible. Sharing data improves visibility, and makes the research process transparent. This increases trust in the work, and allows for independent reproduction of results. However, a large proportion of data from published research is often only available to the original authors. Despite the obvious benefits of sharing data, and scientists' advocating for the importance of sharing data, most advice on sharing data discusses its broader benefits, rather than the practical considerations of sharing. This paper provides practical, actionable advice on how to actually share data alongside research. The key message is sharing data falls on a continuum, and entering it should come with minimal barriers.