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CRISPR Gene Editing in Human Embryos Wreaks Chromosomal Mayhem

CRISPR Gene Editing in Human Embryos Wreaks Chromosomal Mayhem

Three studies showing large DNA deletions and reshuffling heighten safety concerns about heritable genome editing.

Overcoming Barriers to Cross-cultural Cooperation in AI Ethics and Governance

Overcoming Barriers to Cross-cultural Cooperation in AI Ethics and Governance

Achieving the global benefits of artificial intelligence (AI) will require international cooperation on many areas of governance and ethical standards, while allowing for diverse cultural perspectives and priorities.

Impact factor volatility due to a single paper: A comprehensive analysis

Impact factor volatility due to a single paper: A comprehensive analysis

This publication shows how a single paper affects the impact factor (IF) of a journal by analyzing data from 3,088,511 papers published in 11639 journals in the 2017 Journal Citation Reports of Clarivate Analytics.

The Diversity-Innovation Paradox in Science

The Diversity-Innovation Paradox in Science

This paper finds that demographically underrepresented students innovate at higher rates than majority students, but their novel contributions are discounted and less likely to earn them academic positions.

Does Tweeting Improve Citations? One-Year Results from the TSSMN Prospective Randomized Trial

Does Tweeting Improve Citations? One-Year Results from the TSSMN Prospective Randomized Trial

This study aims to evaluate the 1-year results of a prospective randomized social media trial to determine the effect of tweeting on subsequent citations and non-traditional bibliometrics.

Forecasting for COVID-19 Has Failed - International Institute of Forecasters

Forecasting for COVID-19 Has Failed - International Institute of Forecasters

COVID-19 is a major acute crisis with unpredictable consequences. Many scientists have struggled to make forecasts about its impact. However, despite involving many excellent modelers, best intentions, and highly sophisticated tools, forecasting efforts have largely failed.

NIH Peer Review: Criterion Scores Completely Account for Racial Disparities in Overall Impact Scores

NIH Peer Review: Criterion Scores Completely Account for Racial Disparities in Overall Impact Scores

Study found that preliminary criterion scores fully account for racial disparities - yet do not explain all of the variability - in preliminary overall impact scores.

New Report Will Support UKRI's Commitment to Strengthening Research Integrity and Culture

New Report Will Support UKRI's Commitment to Strengthening Research Integrity and Culture

Personal integrity and local culture are key to research integrity, and bullying and harassment is the single biggest negative influence, according to a new study by UK Research and Innovation (UKRI).

How COVID-19 is Changing Research Culture

How COVID-19 is Changing Research Culture

The research world has moved faster than many would have suspected possible in response to the COVID-19 pandemic. In five months, a volume of work has been generated that even the most intensive of emergent fields have taken years to create.In our new report, How COVID-19 is Changing Research Culture, we investigate the research landscape trends and cultural changes in response to COVID-19. The report includes analysis of publication trends, geographic focal points of research, and collaboration patterns.

Estimating the Effects of Non-pharmaceutical Interventions on COVID-19 in Europe

Estimating the Effects of Non-pharmaceutical Interventions on COVID-19 in Europe

What was the impact of non-pharmaceutical interventions at the outset of the pandemic?

Preprinting a Pandemic: the Role of Preprints in the COVID-19 Pandemic

Preprinting a Pandemic: the Role of Preprints in the COVID-19 Pandemic

Analysis of over 16,000 preprints released within 4 months of the first confirmed case found that COVID-19 preprints are shorter, with fewer panels and tables, and reviewed faster.

Reaching out: science communication in times of pandemic

Reaching out: science communication in times of pandemic

In the midst of the COVID-19 pandemic, science is crucial to inform public policy. At the same time, mistrust of scientists and misinformation about scientific facts are rampant. Six scientists, actively involved in outreach, reflect on how to build a better understanding and trust of science.

Estimating the Burden of SARS-CoV-2 in France

Estimating the Burden of SARS-CoV-2 in France

France has been heavily affected by the SARS-CoV-2 epidemic and went into lockdown on the 17 March 2020. Using models applied to hospital and death data, we estimate the impact of the lockdown and current population immunity. 

There is No Black and White Definition of Predatory Publishing

There is No Black and White Definition of Predatory Publishing

Predatory publishing has emerged as a professional problem for academics and their institutions, as well as a broader societal concern, bringing to the fore a debate over what constitutes legitimate science.

Purposes of Peer Review: A Qualitative Study of Stakeholder Expectations and Perceptions

Purposes of Peer Review: A Qualitative Study of Stakeholder Expectations and Perceptions

Authors, editors and publishers differ in their understanding of and the value they attach to the purposes of peer review. 

Beyond sex and gender analysis: an intersectional view of the COVID-19 pandemic outbreak and response

Beyond sex and gender analysis: an intersectional view of the COVID-19 pandemic outbreak and response

In this COVID-19 pandemic, emerging popular refrains like ‘we’re all in this together’ and ‘we will come through this together’
echo across media. But who is this ‘we’?

Spike Mutation Pipeline Reveals the Emergence of a More Transmissible Form of SARS-CoV-2

Spike Mutation Pipeline Reveals the Emergence of a More Transmissible Form of SARS-CoV-2

We have developed an analysis pipeline to facilitate real-time mutation tracking in SARS-CoV-2, focusing initially on the Spike (S) protein because it mediates infection of human cells and is the target of most vaccine strategies and antibody-based therapeutics.

Google Scholar, Microsoft Academic, Scopus, Dimensions, Web of Science, and OpenCitations' COCI: a Multidisciplinary Comparison of Coverage Via Citations

Google Scholar, Microsoft Academic, Scopus, Dimensions, Web of Science, and OpenCitations' COCI: a Multidisciplinary Comparison of Coverage Via Citations

New sources of citation data have recently become available. Although these have been compared to the Web of Science (WoS), Scopus, or Google Scholar, there is no systematic evidence of their differences across subject categories. In response, this paper investigates citations found by these data sources to English-language highly-cited documents published in 2006 from 252 subject categories, expanding and updating the largest previous study.

The Limitations to Our Understanding of Peer Review

The Limitations to Our Understanding of Peer Review

Peer review is embedded in the core of our knowledge generation systems. Despite its critical importance, it curiously remains poorly understood in a number of dimensions. In order to address this, this paper assesses where the major gaps in the theoretical and empirical understanding of peer review lie. 

A Systematic Examination of Preprint Platforms for Use in the Medical and Biomedical Sciences Setting

A Systematic Examination of Preprint Platforms for Use in the Medical and Biomedical Sciences Setting

The objective of this review is to identify all preprint platforms with biomedical and medical scope and to compare and contrast the key characteristics and policies of these platforms.

Arbitrariness in the Peer Review Process

Arbitrariness in the Peer Review Process

The study replicates the NIPS experiment of 2014, showing that the ratings of peer review are not robust, and that altering reviewers leads to a dramatic impact on the ranking of the papers. This paper also shows that innovative works are not highly ranked in the existing peer review process, and in consequence are often rejected.

Extraordinary Diseases Require Extraordinary Solutions

Extraordinary Diseases Require Extraordinary Solutions

The world is experiencing a major pandemic with a high mor-tality. One can hope that the outbreak will end spontaneously aftermost people are infected, but the SARS-2 coronavirus may becomeendemic and continue to cause cycles of respiratory disease andfatal pneumonias.

Projecting the Transmission Dynamics of SARS-CoV-2 Through the Postpandemic Period

Projecting the Transmission Dynamics of SARS-CoV-2 Through the Postpandemic Period

It is urgent to understand the future of severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) transmission. This research group used estimates of seasonality, immunity, and cross-immunity for betacoronaviruses OC43 and HKU1 from time series data from the USA to inform a model of SARS-CoV-2 transmission.

A Realistic Guide to Making Data Available Alongside Code to Improve Reproducibility

A Realistic Guide to Making Data Available Alongside Code to Improve Reproducibility

Data makes science possible. Sharing data improves visibility, and makes the research process transparent. This increases trust in the work, and allows for independent reproduction of results. However, a large proportion of data from published research is often only available to the original authors. Despite the obvious benefits of sharing data, and scientists' advocating for the importance of sharing data, most advice on sharing data discusses its broader benefits, rather than the practical considerations of sharing. This paper provides practical, actionable advice on how to actually share data alongside research. The key message is sharing data falls on a continuum, and entering it should come with minimal barriers.