Scientists should consider engaging more with the DIYbio community.

Two years in, a $1-billion-plus effort to simulate the human brain is in disarray. Was it poor management, or is something fundamentally wrong with Big Science?

Laura and John Arnold, a Houston couple, have become the Medicis for "research integrity". They finance the Center of Open Science (COS) and the METRICS Institute led by J.P. Ioannidis at Stanford.

Crowdsourcing research can balance discussions, validate findings and better inform policy.

A debate is growing in the research world over the value of replicating older, peer-reviewed studies.

Humans are remarkably good at self-deception. But growing concern about reproducibility is driving many researchers to seek ways to fight their own worst instincts.

Major awards honor the scientists who are usually in the least need of recognition and funding, which squeezes out opportunities for other scientists.

The 2015 Nobel Prize in Physiology or Medicine has gone to a researcher who spent her entire career researching traditional Chinese medicine...

Is "Precision Medicine" another case of rebranding, as chemistry has morphed into nanotech?

A massive increase in the power of digital technology over the past decade allows us today to publish any article, blog post or tweet in a matter of seconds.

The lead paper describing Homo naledi has been viewed more than 170,000 times in one week.

To me, volunteering your time means forgoing payment for your time. But how is this affected when someone else is cashing in on your time instead?

[19]PubPeer is a bit like an extended journal club; not a bad idea to promote communication among scientists, you might think, so why the controversy?

Would we be possibly be better off without any patents at all?

Too many university posts are given to men without proper competition.

"I'm not a scientist." How many times have you heard that lately from politicians who are trying to duck questions about important scientific topics like climate change and vaccines?

What does 'excellence' really mean?

We need to ensure the reward and support structures in academia promote the best practices rather than corner cutting.

STEM culture must rein in the pressure to separate professional and personal identities.

Turn the fraught flirtation between the social and biophysical sciences into fruitful partnerships with five principles.

Bernard Rentier explains how the University of Liege persuaded nearly all its researchers to put their papers in its institutional repository.

Please, European universities, stop playing in the second league when it comes to fundraising. Go out and ask your alumni for resources to help you build the next Stanford.

Paul Jump examines the many reasons for irreproducibility in science and efforts to tackle it.

In the US, taxpayers are said to be spending $139bn a year on research, and in the UK, £4.7bn. Too much of that money is disappearing into big pockets.

UK Minister for Universities and Science Jo Johnson wants to see a "simpler" research funding system as well as faster routes for private provider "challenger institutions" to enter higher education.

Peer review is often claimed to be the guarantor of the trustworthiness of scientific papers, but it is a troubled process. Preprints offer a way out.

University league tables do not pay enough attention to institutions’ innovative spirit, argues the European Commission’s Gerard de Graaf.

Tie funding to verified good institutional practice, and robust science will shoot up the agenda.

Failure to replicate is not a bug; it is a feature. It is what leads us along the path of scientific discovery.

My team is drawn from all over Europe and beyond – the researchers bring in talent, income and dedication.